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VKAs, predominantly warfarin, have traditionally been used and recommended for the prevention and treatment of LV thrombus. OAC with warfarin, however, requires dietary consistency, frequent INR monitoring, and vigilance with regard to drug-food (and drug-drug) .¢= @bp ‹ d©Y©_!@»ƒ¬ø˜lêf¶×Gb3æ unyKÒÙr® ƒ ¾îãI¾˜^ .We would like to show you a description here but the site won’t allow us.¢= @bp ‹ d©Y©_!@»ƒ¬ø˜lêf¶×Gb3æ unyKÒÙr® ƒ ¾îãI¾˜^ .
Left ventricular (LV) thrombus formation is a well‐known complication in the course of .
eLetters should relate to an article recently published in the journal and are not a .
We sought to determine whether an association existed between the . While warfarin has been standard of care for management of LV thrombus, convenience of DOAC administration makes them an attractive alternative for many patients. .
Our results suggest that apixaban is non-inferior to warfarin for treatment of patients with LV thrombus after acute MI with a 20% non-inferiority margin. VKAs, predominantly warfarin, have traditionally been used and recommended for the prevention and treatment of LV thrombus. OAC with warfarin, however, requires dietary consistency, frequent INR monitoring, and vigilance with regard to drug-food (and drug-drug) interactions that can be challenging for many patients. While warfarin has been standard of care for management of LV thrombus, convenience of DOAC administration makes them an attractive alternative for many patients. This retrospective cohort study questions the efficacy of DOAC therapy as compared to warfarin.
Our results suggest that apixaban is non-inferior to warfarin for treatment of patients with LV thrombus after acute MI with a 20% non-inferiority margin. On the basis of supportive though insufficiently powered randomized data, in patients with LV thrombus, DOAC seems to be a reasonable alternative to warfarin. Left ventricular thrombus (LVT) is not uncommon and pose a risk of systemic embolism, which can be mitigated by adequate anticoagulation. Direct oral anticoagulants (DOACs) are increasingly being used as alternatives to warfarin for anticoagulation, but their efficacy and safety profile has been debated.Left ventricular (LV) thrombus is a feared complication of LV dysfunction associated with high rates of systemic embolism, morbidity, and mortality. Traditionally, LV thrombus has been associated with acute myocardial infarction (MI).
We compared the rates of thrombus persistence and stroke or systemic embolism (SSE) in patients diagnosed with an LV thrombus and treated with either warfarin or DOAC at a tertiary academic medical center. Left ventricular thrombus (LVT) is associated with a significant risk of ischemic stroke (IS) and peripheral embolization. Societal guidelines recommend the use of warfarin, with direct oral anticoagulants (DOACs) only for patients unable to tolerate warfarin.
The advent of reperfusion therapy and the widespread use of primary percutaneous coronary intervention (PCI) have markedly reduced the incidence of post–myocardial infarction (MI) left ventricular thrombus (LVT) over the last decades (1–3).
Current guidelines recommend anticoagulation with a vitamin K antagonist to treat left ventricular (LV) thrombus after myocardial infarction (MI). Data on the use of direct oral anticoagulants (DOACs) in this setting are limited. The aim of the study was to assess the efficacy of apixaban vs. warfarin in treating LV thrombus after MI.
VKAs, predominantly warfarin, have traditionally been used and recommended for the prevention and treatment of LV thrombus. OAC with warfarin, however, requires dietary consistency, frequent INR monitoring, and vigilance with regard to drug-food (and drug-drug) interactions that can be challenging for many patients. While warfarin has been standard of care for management of LV thrombus, convenience of DOAC administration makes them an attractive alternative for many patients. This retrospective cohort study questions the efficacy of DOAC therapy as compared to warfarin.
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Our results suggest that apixaban is non-inferior to warfarin for treatment of patients with LV thrombus after acute MI with a 20% non-inferiority margin. On the basis of supportive though insufficiently powered randomized data, in patients with LV thrombus, DOAC seems to be a reasonable alternative to warfarin.
Left ventricular thrombus (LVT) is not uncommon and pose a risk of systemic embolism, which can be mitigated by adequate anticoagulation. Direct oral anticoagulants (DOACs) are increasingly being used as alternatives to warfarin for anticoagulation, but their efficacy and safety profile has been debated.Left ventricular (LV) thrombus is a feared complication of LV dysfunction associated with high rates of systemic embolism, morbidity, and mortality. Traditionally, LV thrombus has been associated with acute myocardial infarction (MI).We compared the rates of thrombus persistence and stroke or systemic embolism (SSE) in patients diagnosed with an LV thrombus and treated with either warfarin or DOAC at a tertiary academic medical center. Left ventricular thrombus (LVT) is associated with a significant risk of ischemic stroke (IS) and peripheral embolization. Societal guidelines recommend the use of warfarin, with direct oral anticoagulants (DOACs) only for patients unable to tolerate warfarin.
The advent of reperfusion therapy and the widespread use of primary percutaneous coronary intervention (PCI) have markedly reduced the incidence of post–myocardial infarction (MI) left ventricular thrombus (LVT) over the last decades (1–3).
lv thrombus treatment timeline
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lv thrombus warfarin|lv thrombus treatment timeline
